Burden of Neisseria meningitidis infections in China: a systematic review and meta-analysis.

ABSTRACT:

Background

Neisseria meningitidis is a leading cause of bacterial meningitis and septicemia in children and young adults worldwide. The disease burden associated with N. meningitidis infections has not been systematically assessed in China. Therefore, we undertook this study to determine the burden of meningococcal disease in China.

Method

We performed a systematic review and meta-analysis of articles on N. meningitidis incidence, carriage, seroprevalence and mortality rates in China by searching the Chinese BioMedical Database (CBM), China National Knowledge Infrastructure (CNKI), Wanfang database and PubMed for publications from January 2005 to Aug 2015.

Results

In total, 50 articles were included in our analysis. The overall incidence of mening

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC5112005 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature