Antisocial peer affiliation and externalizing disorders: Evidence for Gene × Environment × Development interaction.

ABSTRACT: Gene × Environment interaction contributes to externalizing disorders in childhood and adolescence, but little is known about whether such effects are long lasting or present in adulthood. We examined gene-environment interplay in the concurrent and prospective associations between antisocial peer affiliation and externalizing disorders (antisocial behavior and substance use disorders) at ages 17, 20, 24, and 29. The sample included 1,382 same-sex twin pairs participating in the Minnesota Twin Family Study. We detected a Gene × Environment interaction at age 17, such that additive genetic influences on antisocial behavior and substance use disorders were greater in the context of greater antisocial peer affiliation. This Gene × Environment interaction was not present for antisocial behavio

SUBMITTER: Samek DR 

PROVIDER: S-EPMC5112158 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature