Diversity, evolution and expression profiles of histone acetyltransferases and deacetylases in oomycetes.

ABSTRACT:

Background

Oomycetes are a group of fungus-like eukaryotes with diverse microorganisms living in marine, freshwater and terrestrial environments. Many of them are important pathogens of plants and animals, causing severe economic losses. Based on previous study, gene expression in eukaryotic cells is regulated by epigenetic mechanisms such as DNA methylation and histone modification. However, little is known about epigenetic mechanisms of oomycetes.

Results

In this study, we investigated the candidate genes in regulating histone acetylation in oomycetes genomes through bioinformatics approaches and identified a group of diverse histone acetyltransferases (HATs) and histone deacetylases (HDACs), along with three putative novel HATs. Phylogenetic analyses suggested that most o

SUBMITTER: Wang XW 

PROVIDER: S-EPMC5112689 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature