The effect of preoperative dexamethasone on pain 1 year after lumbar disc surgery: a follow-up study.

ABSTRACT:

Background

It has been hypothesized that dexamethasone can inhibit persistent postoperative pain, but data on humans is lacking and results from animal studies are conflicting. We explored the effect of 16 mg dexamethasone IV administered preoperatively on persistent pain 1 year after lumbar discectomy.

Methods

This is a prospective 1-year follow-up on a single-centre, randomized, and blinded trial exploring the analgesic effect of 16 mg IV dexamethasone or placebo after lumbar discectomy. One year follow-up was a written questionnaire including back and leg pain (VAS 0-100 mm), Short Form 36 survey (SF-36), EuroQol 5D (EQ-5D), OSWESTRY Low Back Pain Questionnaire, duration of sick leave, working capability, contentment with surgical result.

Results

Response rate was

SUBMITTER: Nielsen RV 

PROVIDER: S-EPMC5112723 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature