Forms and Amounts of Vitamin B12 in Infant Formula: A Pilot Study.

ABSTRACT:

Purpose

Infant formula is based on cow's milk and designed to mimic breast milk for substitution. Vitamin B12 (B12) is bound to proteins in both breast milk and cow's milk, and in milk from both species the vitamin occurs mainly in its natural form such as hydroxo-B12 with little or no synthetic B12 (cyano-B12). Here we test commercially available infant formulas.

Methods

Eleven commercially available infant formulas were measured for content of B12 and analyzed for the presence of B12-binding proteins and forms of B12 using size exclusion chromatography and HPLC.

Results

All infant formulas contained B12 by and large in accord with the informations given on the package inserts. None of the formulas contained protein-bound B12, and cyano-B12 accounted for 19-78% of th

SUBMITTER: Greibe E 

PROVIDER: S-EPMC5112923 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature