Minimally Symptomatic Infection in an Ebola 'Hotspot': A Cross-Sectional Serosurvey.

ABSTRACT:

Introduction

Evidence for minimally symptomatic Ebola virus (EBOV) infection is limited. During the 2013-16 outbreak in West Africa, it was not considered epidemiologically relevant to published models or projections of intervention effects. In order to improve our understanding of the transmission dynamics of EBOV in humans, we investigated the occurrence of minimally symptomatic EBOV infection in quarantined contacts of reported Ebola virus disease cases in a recognized 'hotspot.'

Methodology/principal findings

We conducted a cross-sectional serosurvey in Sukudu, Kono District, Sierra Leone, from October 2015 to January 2016. A blood sample was collected from 187 study participants, 132 negative controls (individuals with a low likelihood of previous exposure to Ebola viru

SUBMITTER: Richardson ET 

PROVIDER: S-EPMC5112953 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature