Predictors of Pregnancy Outcomes in Patients With Lupus: A Cohort Study.

ABSTRACT:

Background

Because systemic lupus erythematosus (SLE) affects women of reproductive age, pregnancy is a major concern.

Objective

To identify predictors of adverse pregnancy outcomes (APOs) in patients with inactive or stable active SLE.

Design

Prospective cohort.

Setting

Multicenter.

Patients

385 patients (49% non-Hispanic white; 31% with prior nephritis) with SLE in the PROMISSE (Predictors of Pregnancy Outcome: Biomarkers in Antiphospholipid Antibody Syndrome and Systemic Lupus Erythematosus) study. Exclusion criteria were urinary protein-creatinine ratio greater than 1000 mg/g, creatinine level greater than 1.2 mg/dL, prednisone use greater than 20 mg/d, and multifetal pregnancy.

Measurements

APOs included fetal or neonatal death; birth before

SUBMITTER: Buyon JP 

PROVIDER: S-EPMC5113288 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature