Ancestral population reconstitution from isofemale lines as a tool for experimental evolution.

ABSTRACT: Experimental evolution is a powerful tool to study adaptation under controlled conditions. Laboratory natural selection experiments mimic adaptation in the wild with better-adapted genotypes having more offspring. Because the selected traits are frequently not known, adaptation is typically measured as fitness increase by comparing evolved populations against an unselected reference population maintained in a laboratory environment. With adaptation to the laboratory conditions and genetic drift, however, it is not clear to what extent such comparisons provide unbiased estimates of adaptation. Alternatively, ancestral variation could be preserved in isofemale lines that can be combined to reconstitute the ancestral population. Here, we assess the impact of selection on alleles segregating i

SUBMITTER: Nouhaud P 

PROVIDER: S-EPMC5114691 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature