Residual Kidney Function Decline and Mortality in Incident Hemodialysis Patients.

ABSTRACT: In patients with ESRD, residual kidney function (RKF) contributes to achievement of adequate solute clearance. However, few studies have examined RKF in patients on hemodialysis. In a longitudinal cohort of 6538 patients who started maintenance hemodialysis over a 4-year period (January 2007 through December 2010) and had available renal urea clearance (CL_urea) data at baseline and 1 year after hemodialysis initiation, we examined the association of annual change in renal CL_urea rate with subsequent survival. The median (interquartile range) baseline value and mean±SD annual change of CL_urea were 3.3 (1.9-5.0) and -1.1±2.8 ml/min per 1.73 m², respectively. Greater CL_urea rate 1 year after hemodialysis initiation associated with better

SUBMITTER: Obi Y 

PROVIDER: S-EPMC5118484 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature