Comparison of internal target volumes defined on 3-dimensional, 4-dimensonal, and cone-beam CT images of non-small-cell lung cancer.

ABSTRACT:

Purpose

The purpose of this study was to compare the positional and volumetric differences of internal target volumes defined on three-dimensional computed tomography (3DCT), four-dimensional CT (4DCT), and cone-beam CT (CBCT) images of non-small-cell lung cancer (NSCLC).

Materials and methods

Thirty-one patients with NSCLC sequentially underwent 3DCT and 4DCT simulation scans of the thorax during free breathing. The first CBCT was performed and registered to the planning CT using the bony anatomy registration during radiotherapy. The gross tumor volumes were contoured on the basis of 3DCT, maximum intensity projection (MIP) of 4DCT, and CBCT. CTV_3D (clinical target volume), internal target volumes, ITV_MIP and ITV_CBCT, were defined with a 7 m

SUBMITTER: Li F 

PROVIDER: S-EPMC5119621 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature