First Case of Actinomycetoma in France Due to a Novel Nocardia Species, Nocardia boironii sp. nov.

ABSTRACT: Bacterial mycetoma is a neglected disease mainly observed in tropical area countries and typically associated with rural conditions, making its presence in developed countries of temperate climate areas rare. However, we report the first case of an autochthonous mycetoma case in continental France that originated from a new Nocardia species. A Gram-positive filamentous bacterium (OFN 14.177T) was isolated from a pus sample from the mycetoma of a male French patient 92 years old suffering from chronic lymphocytic leukemia. The isolate was analyzed by a polyphasic taxonomic approach by coupling morphological, biochemical, physiological, and chemotaxonomic aspects to genomic and phylogenetic analyses. Multilocus sequence analysis (MLSA) using four housekeeping genes (16S rRNA gene, secA1, hsp

SUBMITTER: Gilquin JM 

PROVIDER: S-EPMC5120171 | biostudies-literature | 2016 Nov-Dec

REPOSITORIES: biostudies-literature