Physical activity and metabolic health in chronic kidney disease: a cross-sectional study.

ABSTRACT:

Background

Patients with chronic kidney disease (CKD) are at high risk of progression to end stage renal disease and cardiovascular events. Physical activity may reduce these risks by improving metabolic health. We tested associations of physical activity with central components of metabolic health among people with moderate-severe non-diabetic CKD.

Methods

We performed a cross-sectional study of 47 people with CKD (estimated GFR <60 ml/min/1.73 m²) and 29 healthy control subjects. Accelerometry was used to measured physical activity over 7 days, the hyperinsulinemic-euglycemic clamp was used to measure insulin sensitivity, and DXA was used to measured fat mass. We tested associations of physical activity with insulin sensitivity, fat mass, blood pressure, serum l

SUBMITTER: Bowlby W 

PROVIDER: S-EPMC5120456 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature