Baseline Fourier-Domain Optical Coherence Tomography Structural Risk Factors for Visual Field Progression in the Advanced Imaging for Glaucoma Study.

ABSTRACT:

Purpose

To identify baseline structural parameters that predict the progression of visual field (VF) loss in patients with open-angle glaucoma.

Design

Multicenter cohort study.

Methods

Participants from the Advanced Imaging for Glaucoma (AIG) study were enrolled and followed up. VF progression is defined as either a confirmed progression event on Humphrey Progression Analysis or a significant (P < .05) negative slope for VF index (VFI). Fourier-domain optical coherence tomography (FDOCT) was used to measure optic disc, peripapillary retinal nerve fiber layer (NFL), and macular ganglion cell complex (GCC) thickness parameters.

Results

A total of 277 eyes of 188 participants were followed up for 3.7 ± 2.1 years. VF progression was observed in 83 eyes (30%). Sever

SUBMITTER: Zhang X 

PROVIDER: S-EPMC5121039 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature