Parent-mediated social communication therapy for young children with autism (PACT): long-term follow-up of a randomised controlled trial.

ABSTRACT:

Background

It is not known whether early intervention can improve long-term autism symptom outcomes. We aimed to follow-up the Preschool Autism Communication Trial (PACT), to investigate whether the PACT intervention had a long-term effect on autism symptoms and continued effects on parent and child social interaction.

Methods

PACT was a randomised controlled trial of a parent-mediated social communication intervention for children aged 2-4 years with core autism. Follow-up ascertainment was done at three specialised clinical services centres in the UK (London, Manchester, and Newcastle) at a median of 5·75 years (IQR 5·42-5·92) from the original trial endpoint. The main blinded outcomes were the comparative severity score (CSS) from the Autism Diagnostic Observation Schedul

SUBMITTER: Pickles A 

PROVIDER: S-EPMC5121131 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature