Bifurcation Type and Larger Low Shear Area Are Associated with Rupture Status of Very Small Intracranial Aneurysms.

ABSTRACT:

Background

Characterization of the risk factors for rupture of very small intracranial aneurysm (VSIA, ≤3 mm) is clinically valuable, since VSIAs are implicated in subarachnoid hemorrhage. The aim of this study was to identify morphological and hemodynamic parameters that independently characterize the rupture status of VSIAs.

Methods

We conducted a retrospective study of consecutive VSIAs between September 2010 and February 2014 in our institute. A series of morphologic and hemodynamic parameters were evaluated using computational fluid dynamics, based on patient-specific three-dimensional geometrical models.

Results

We identified 186 patients with 206 VSIAs (73 ruptured, 133 unruptured). Univariable logistic regression analysis showed that bifurcation type, parent a

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC5121469 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature