Delayed Time to Peak Velocity Is Useful for Detecting Severe Aortic Stenosis.

ABSTRACT:

Background

Time to peak velocity (TPV) is an echocardiographic variable that can be easily measured and reflects a late peaking murmur, a classic physical finding suggesting severe aortic stenosis (AS). The aim of this study was to investigate the usefulness of TPV to evaluate AS severity.

Methods and results

This study included 700 AS patients, whose aortic valve area (AVA) was <1.5 cm², and 200 control patients. The TPV was defined as the time from aortic valve opening to when the flow velocity across the aortic valve reaches its peak. AS severity was classified as follows: High gradient severe AS, mean pressure gradient ≥40 mm Hg and AVA index (AVAI) <0.6 cm²/m²; Low gradient severe AS, mean pressure gradient <40 mm Hg, AVAI <0.6 cm^2<

SUBMITTER: Kamimura D 

PROVIDER: S-EPMC5121493 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature