Risk Factors for Barrett's Oesophagus.

ABSTRACT:

Background

Barrett's oesophagus (BO) is a premalignant condition associated with the development of oesophageal adenocarcinoma (OAC). Globally, the incidence of OAC is rising. Furthermore, the prognosis regarding the morbidity and mortality of OAC is bleak, with an estimated 5-year survival of 10-15%. Hence, detection of the premalignant phase is paramount. Endoscopy and biopsy sampling is the mainstay of diagnosis. Patients may present with symptoms of gastro-oesophageal reflux disease (GORD) or be completely asymptomatic. Therefore, symptomatology alone is a poor indicator of this condition.

Summary

This review highlights the current risk factors associated with the development of BO.

Key message

Primary risk factors for BO include male gender, increased age, a fami

SUBMITTER: Sharma N 

PROVIDER: S-EPMC5121541 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature