Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis.

ABSTRACT:

Objective

To determine if serum levels of endothelial adhesion molecules were associated with the development of multiple organ failure (MOF) and in-hospital mortality in adult patients with severe sepsis.

Design

This study was a secondary data analysis of a prospective cohort study.

Setting

Patients were admitted to two tertiary intensive care units in San Antonio, TX, between 2007 and 2012.

Patients

Patients with severe sepsis at the time of intensive care unit (ICU) admission were enrolled. Inclusion criteria were consistent with previously published criteria for severe sepsis or septic shock in adults. Exclusion criteria included immunosuppressive medications or conditions.

Interventions

None.

Measurements

Baseline serum levels of the followin

SUBMITTER: Amalakuhan B 

PROVIDER: S-EPMC5121929 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature