Integrated safety and efficacy analysis of once-daily fluticasone furoate for the treatment of asthma.

ABSTRACT:

Background

Fluticasone furoate is a once-daily inhaled corticosteroid. This report provides an overview of safety and efficacy data that support the use of once-daily fluticasone furoate 100 μg or 200 μg in adult and adolescent asthma patients.

Methods

Fourteen clinical studies (six Phase II and eight Phase III) were conducted as part of the fluticasone furoate global clinical development programme in asthma. Safety data from 10 parallel-group, randomised, double-blind Phase II and III studies (including 3345 patients who received at least one dose of fluticasone furoate) were integrated to provide information on adverse events, withdrawals, laboratory assessments, vital signs and hypothalamic-pituitary-adrenal axis function. The efficacy of once-daily fluticasone furoate wa

SUBMITTER: O'Byrne PM 

PROVIDER: S-EPMC5122018 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature