Inappropriate Prescription and Renal Function Among Older Patients with Cognitive Impairment.

ABSTRACT:

Background

Older people are more sensitive to drugs and adverse drug reactions than younger people because of age-related physiological changes such as impaired renal function. As people with dementia are particularly vulnerable to the effects of drugs, it is especially important to evaluate the dosages of renally cleared medications in this group.

Objective

The aim of this study was to estimate the prevalence of impaired renal function and inappropriate prescriptions on the basis of renal function among older patients with dementia or cognitive impairment.

Methods

The medical records of 428 patients aged ≥65 years who were admitted to two hospitals in northern Sweden were reviewed and renally cleared medications were identified. The Cockcroft-Gault equation was used

SUBMITTER: Sonnerstam E 

PROVIDER: S-EPMC5122609 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature