Longitudinal Course of Bipolar Disorder in Youth With High-Functioning Autism Spectrum Disorder.

ABSTRACT:

Objective

To provide the first longitudinal characterization of mood and psychosocial functioning in youth with comorbid bipolar (BD) and autism spectrum (ASD) disorders.

Method

The Course and Outcome of Bipolar Youth study followed 368 youth (aged 7-17 years) with DSM-IV bipolar I (BP-I), BP-II, or Not Otherwise Specified (NOS) for, on average, 9 years using the Longitudinal Interval Follow-up Evaluation. This subgroup analysis compared youth with and without ASD on clinical presentation, percentage of time with mood symptomatology, and psychosocial functioning.

Results

Thirty youth (∼8%) met DSM-IV criteria for Asperger's disorder or pervasive developmental disorder-NOS (referred to here as ASD). Lifetime worst episode severity was similar in both groups, but youth

SUBMITTER: Borue X 

PROVIDER: S-EPMC5123749 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature