Cytotoxic effects of ergone, a compound isolated from Fulviformes fastuosus.

ABSTRACT:

Background

Mushrooms inspired the cuisines of many cultures and conventional medicaments for cancer. However, a substantial number of mushroom species are yet unexplored, possessing an unknown chemical, biological and pharmacological profiles. Fulviformes fastuosus is a terrestrial mushroom, which is commonly found in Sri Lankan woodlands. The current study was aimed at isolation and characterization of a potent cytotoxic compound from F. fastuosus and investigating the apoptotic effect induced by the active principle against cancer and normal cell lines.

Methods

Bioactivity guided isolation of active principles from the methanol extract of F. fastuosus was performed by a rapid extraction and isolation method using different chromatographic techniques. Potential cytotoxic co

SUBMITTER: Fernando D 

PROVIDER: S-EPMC5124230 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature