A new method of finding groups of coexpressed genes and conditions of coexpression.

ABSTRACT:

Background

To study a biological phenomenon such as finding mechanism of disease, common methodology is to generate the microarray data in different relevant conditions and find groups of genes co-expressed across conditions from such data. These groups might enable us to find biological processes involved in a disease condition. However, more detailed understanding can be made when information of a biological process associated with a particular condition is obtained from the data. Many algorithms are available which finds groups of co-expressed genes and associated conditions of co-expression that can help finding processes associated with particular condition. However, these algorithms depend on different input parameters for generating groups. For real datasets, it is difficult

SUBMITTER: Anand R 

PROVIDER: S-EPMC5124285 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature