Continuous EEG monitoring enhances multimodal outcome prediction in hypoxic-ischemic brain injury.

ABSTRACT:

Objective

Hypoxic brain injury is the largest contributor to disability and mortality after cardiac arrest. We aim to identify electroencephalogram (EEG) characteristics that can predict outcome on cardiac arrest patients treated with targeted temperature management (TTM).

Methods

We retrospectively examined clinical, EEG, functional outcome at discharge, and in-hospital mortality for 373 adult subjects with return of spontaneous circulation after cardiac arrest. Poor outcome was defined as a Cerebral Performance Category score of 3-5. Pure suppression-burst (SB) was defined as SB not associated with status epilepticus (SE), seizures, or generalized periodic discharges.

Results

In-hospital mortality was 68.6% (N=256). Presence of both unreactive EEG background and SE

SUBMITTER: Amorim E 

PROVIDER: S-EPMC5124407 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature