Tailoring Breast Cancer Screening Intervals by Breast Density and Risk for Women Aged 50 Years or Older: Collaborative Modeling of Screening Outcomes.

ABSTRACT:

Background

Biennial screening is generally recommended for average-risk women aged 50 to 74 years, but tailored screening may provide greater benefits.

Objective

To estimate outcomes for various screening intervals after age 50 years based on breast density and risk for breast cancer.

Design

Collaborative simulation modeling using national incidence, breast density, and screening performance data.

Setting

United States.

Patients

Women aged 50 years or older with various combinations of breast density and relative risk (RR) of 1.0, 1.3, 2.0, or 4.0.

Intervention

Annual, biennial, or triennial digital mammography screening from ages 50 to 74 years (vs. no screening) and ages 65 to 74 years (vs. biennial digital mammography from ages 50 to 64 years).

SUBMITTER: Trentham-Dietz A 

PROVIDER: S-EPMC5125086 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature