Building a model to increase live birth rate through patient-specific optimization of embryo transfer day.

ABSTRACT:

Purpose

Many practices are moving away from cleavage-stage transfer in favor of blastocyst transfer. The purpose of this study is to evaluate how the overall live birth rate for fresh IVF cycles may increase by optimizing the day of transfer for each patient.

Methods

This is a retrospective cohort study of 1225 first fresh autologous IVF cycles performed between May 2012 and November 2013. Stepwise logistic regression was used to determine characteristics associated with live birth following cleavage-stage versus blastocyst transfer. The optimal transfer day (i.e., the day that maximized the odds of live birth) was determined for each patient, and the actual live birth rate was compared with the projected rate had each patient undergone transfer on her optimal day.

Result

SUBMITTER: Goldman RH 

PROVIDER: S-EPMC5125155 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature