Comparative Effectiveness of Smoking Cessation Medications: A National Prospective Cohort From Taiwan.

ABSTRACT:

Background and objective

Relative effectiveness of smoking cessation medications-varenicline, bupropion and nicotine replacement therapy (NRT)-remains unclear among smokers in real-world settings. Evidence in females and smokers with light/moderate nicotine dependence is particularly insufficient. This study compared the effectiveness of varenicline, bupropion or NRT gum relative to NRT patch, in achieving abstinence among recent quitters.

Methods

In a national smoking cessation program in Taiwan (2012-2015), a cohort of 11,968 participants received varenicline (n = 5,052), bupropion (n = 823), NRT gum (n = 1944) or NRT patch (n = 4,149). The 7-day, 1-month or 6-month point-prevalence was calculated based on self-reported last smoking event via telephone interview after 6 mo

SUBMITTER: Chang PY 

PROVIDER: S-EPMC5125644 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature