Impact of Prolonged Temporal Discrimination Threshold on Finger Movements of Parkinson's Disease.

ABSTRACT:

Introduction

Sensory information is essential for the precise control of movement. Patients with Parkinson's disease (PD) have higher-order sensory dysfunctions including prolonged temporal discrimination threshold (TDT). However, the impact of prolonged TDT on parkinsonian motor deficits is uncertain.

Methods

This study includes 33 PD patients and 24 healthy controls. TDT values were measured in the index finger. Using coin rotation task (CRT), dexterous finger movement was assessed. Using an inertial sensor, the speed, amplitude, and frequency of finger tapping were measured. The impact of prolonged index finger TDT on two different finger movements was analyzed using the general estimating equation.

Results

Compared to healthy controls, TDT was prolonged in the PD

SUBMITTER: Lee MJ 

PROVIDER: S-EPMC5125668 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature