Relationships between cortical myeloarchitecture and electrophysiological networks.

ABSTRACT: The human brain relies upon the dynamic formation and dissolution of a hierarchy of functional networks to support ongoing cognition. However, how functional connectivities underlying such networks are supported by cortical microstructure remains poorly understood. Recent animal work has demonstrated that electrical activity promotes myelination. Inspired by this, we test a hypothesis that gray-matter myelin is related to electrophysiological connectivity. Using ultra-high field MRI and the principle of structural covariance, we derive a structural network showing how myelin density differs across cortical regions and how separate regions can exhibit similar myeloarchitecture. Building upon recent evidence that neural oscillations mediate connectivity, we use magnetoencephalography to eluc

SUBMITTER: Hunt BA 

PROVIDER: S-EPMC5127325 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature