The use of varenicline to treat nicotine dependence among patients with cancer.

ABSTRACT:

Background

Continuing to smoke after a cancer diagnosis can adversely influence the prognosis for patients with cancer. However, remarkably few studies have carefully examined the use of first-line FDA-approved medications for nicotine dependence in patients with cancer. This study evaluated the feasibility, safety, and effect on cessation of varenicline for smoking cessation in patients with cancer.

Methods

Data from 132 treatment-seeking smokers who received 12 weeks of open-label varenicline and five brief behavioral counseling sessions were used to evaluate the feasibility, safety, and impact on cessation of varenicline. The effects of abstinence on cognitive function and affect were also explored.

Results

Of 459 patients screened, 306 were eligible for the study

SUBMITTER: Price S 

PROVIDER: S-EPMC5127776 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature