Interaction between Nitrogen and Phosphate Stress Responses in Sinorhizobium meliloti.

ABSTRACT: Bacteria have developed various stress response pathways to improve their assimilation and allocation of limited nutrients, such as nitrogen and phosphate. While both the nitrogen stress response (NSR) and phosphate stress response (PSR) have been studied individually, there are few experiments reported that characterize effects of multiple stresses on one or more pathways in Sinorhizobium meliloti, a facultatively symbiotic, nitrogen-fixing bacteria. The P_II proteins, GlnB and GlnK, regulate the NSR activity, but analysis of global transcription changes in a P_II deficient mutant suggest that the S. meliloti P_II proteins may also regulate the PSR. P_II double deletion mutants grow very slowly and pseudoreversion of the slow growth ph

SUBMITTER: Hagberg KL 

PROVIDER: S-EPMC5127829 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature