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Complication rates of CT-guided transthoracic lung biopsy: meta-analysis.


ABSTRACT:

Objectives

To meta-analyze complication rate in computed tomography (CT)-guided transthoracic lung biopsy and associated risk factors.

Methods

Four databases were searched from 1/2000 to 8/2015 for studies reporting complications in CT-guided lung biopsy. Overall and major complication rates were pooled and compared between core biopsy and fine needle aspiration (FNA) using the random-effects model. Risk factors for complications in core biopsy and FNA were identified in meta-regression analysis.

Results

For core biopsy, 32 articles (8,133 procedures) were included and for FNA, 17 (4,620 procedures). Pooled overall complication rates for core biopsy and FNA were 38.8 % (95 % CI: 34.3-43.5 %) and 24.0 % (95 % CI: 18.2-30.8 %), respectively. Major complication rates wer

SUBMITTER: Heerink WJ 

PROVIDER: S-EPMC5127875 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature