Choice of Moisturiser for Eczema Treatment (COMET): feasibility study of a randomised controlled parallel group trial in children recruited from primary care.

ABSTRACT:

Objectives

To determine the feasibility of a randomised controlled trial of 'leave on' emollients for children with eczema.

Design

Single-centre, pragmatic, 4-arm, observer-blinded, parallel, randomised feasibility trial.

Setting

General practices in the UK.

Participants

Children with eczema aged 1 month to <5 years.

Outcome measures

Primary outcome-proportion of parents who reported use of the allocated study emollient every day for the duration of follow-up (12 weeks). Other feasibility outcomes-participant recruitment and retention, data collection and completeness and blinding of observers to allocation.

Interventions

Aveeno lotion, Diprobase cream, Doublebase gel, Hydromol ointment.

Results

197 children were recruited-107 by self-refer

SUBMITTER: Ridd MJ 

PROVIDER: S-EPMC5129109 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature