Genetic polymorphisms of FAS and EVER genes in a Greek population and their susceptibility to cervical cancer: a case control study.

ABSTRACT:

Background

The aim of the study was to evaluate the association of two SNPs of EVER1/2 genes' region (rs2290907, rs16970849) and the FAS-670 polymorphism with the susceptibility to precancerous lesions and cervical cancer in a Greek population.

Methods

Among the 515 women who were included in the statistical analysis, 113 belong to the case group and present with precancerous lesions or cervical cancer (27 with persistent CIN1, 66 with CIN2/3 and 20 with cervical cancer) and 402 belong to the control group. The chi-squared test was used to compare the case and the control groups with an allelic and a genotype-based analysis.

Results

The results of the statistical analysis comparing the case and the control groups for all the SNPs tested were not statistically signific

SUBMITTER: Pavlidou E 

PROVIDER: S-EPMC5129199 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature