The allergic march comprises the coexistence of related patterns of allergic disease not just the progressive development of one disease.

ABSTRACT:

Aim

This study explored the development and comorbidity of allergic diseases by analysing the relationship between allergic manifestations in infancy and at the age of 8.

Methods

We included 5654 children born in Sweden in 2003 in a longitudinal study. Parents answered postal questionnaires when the children were six months and one, four-and-a-half and eight years of age.

Results

The response rate at eight years was 4051 (71.6%), and we analysed 3382 children with complete data. The number of manifestations in infancy increased the risk of allergic disease at eight years of age: 72% of children with one early manifestation were symptom free at 8, compared to 45% with two or more manifestations. Similar manifestations occurred in infancy and at the age of 8, for exampl

SUBMITTER: Goksor E 

PROVIDER: S-EPMC5129460 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature