Comparative sequence analysis of Cyclospora cayetanensis apicoplast genomes originating from diverse geographical regions.

ABSTRACT:

Background

Cyclospora cayetanensis is an emerging coccidian parasite that causes endemic and epidemic diarrheal disease called cyclosporiasis, and this infection is associated with consumption of contaminated produce or water in developed and developing regions. Food-borne outbreaks of cyclosporiasis have occurred almost every year in the USA since the 1990s. Investigations of these outbreaks are currently hampered due to lack of molecular epidemiological tools for trace back analysis. The apicoplast of C. cayetanensis, a relict non-photosynthetic plastid with an independent genome, provides an attractive target to discover sequence polymorphisms useful as genetic markers for detection and trace back analysis of the parasite. Distinct differences in the apicoplast genomes of C. cay

SUBMITTER: Cinar HN 

PROVIDER: S-EPMC5129617 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature