Preterm Birth during Influenza Season Is Associated with Adverse Outcome in Very Low Birth Weight Infants.

ABSTRACT:

Objective

We investigated the relationship between influenza seasonality and outcome of very low birth weight infants (VLBWI) in a large observational cohort study of the German Neonatal Network.

Materials and methods

Within the observational period (July 2009 until December 2014), five influenza seasons occurred (mean duration: 97 days, range: 48-131 days). We stratified VLBWI (n = 10,187) according to date of birth into three categories: (1) before influenza season, (2) during influenza season, and (3) 3 months after the end of the respective season. Outcomes were assessed in univariate and logistic regression analyses. In a subgroup of infants (n = 1497), the number of respiratory infections during the first 24 months of life was assessed.

Results

VLB

SUBMITTER: Hartel C 

PROVIDER: S-EPMC5129678 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature