Main nutrient patterns and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition study.

ABSTRACT:

Background

Much of the current literature on diet-colorectal cancer (CRC) associations focused on studies of single foods/nutrients, whereas less is known about nutrient patterns. We investigated the association between major nutrient patterns and CRC risk in participants of the European Prospective Investigation into Cancer and Nutrition (EPIC) study.

Methods

Among 477 312 participants, intakes of 23 nutrients were estimated from validated dietary questionnaires. Using results from a previous principal component (PC) analysis, four major nutrient patterns were identified. Hazard ratios (HRs) and 95% confidence intervals (CIs) were computed for the association of each of the four patterns and CRC incidence using multivariate Cox proportional hazards models with adjustment fo

SUBMITTER: Moskal A 

PROVIDER: S-EPMC5129834 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature