Testosterone treatment and risk of venous thromboembolism: population based case-control study.

ABSTRACT:

Objective

 To determine the risk of venous thromboembolism associated with use of testosterone treatment in men, focusing particularly on the timing of the risk.

Design

 Population based case-control study SETTING:  370 general practices in UK primary care with linked hospital discharge diagnoses and in-hospital procedures and information on all cause mortality.

Participants

 19 215 patients with confirmed venous thromboembolism (comprising deep venous thrombosis and pulmonary embolism) and 909 530 age matched controls from source population including more than 2.22 million men between January 2001 and May 2013.

Exposure of interest

 Three mutually exclusive testosterone exposure groups were identified: current treatment, recent (but not current) treatment, and

SUBMITTER: Martinez C 

PROVIDER: S-EPMC5130924 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature