Evaluation of Salvadora persica L. and green tea anti-plaque effect: a randomized controlled crossover clinical trial.

ABSTRACT:

Background

In the author's earlier in vitro investigation, a combination of 0.25 mg/ml green tea and 7.82 mg/ml Salvadora persica L. aqueous extracts was found to exhibit significant synergistic anti-bacterial and anti-adherence effects against primary plaque colonizers biofilm. A clinical trial was needed to support these preliminary in vitro results and to investigate its efficacy as a mouthwash in the control of dental plaque.

Methods

A 24 h plaque re-growth, double-blinded, randomized crossover trial was carried out. Participants (n = 14) randomly rinsed with test formulation, 0.12% chlorhexidine (control) and placebo mouthwashes for 24 h. A week before the trial, all participants received scaling, polishing and oral hygiene education. On the trial day, the participants

SUBMITTER: Abdulbaqi HR 

PROVIDER: S-EPMC5131433 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature