SeqPlots - Interactive software for exploratory data analyses, pattern discovery and visualization in genomics.

ABSTRACT: Experiments involving high-throughput sequencing are widely used for analyses of chromatin function and gene expression. Common examples are the use of chromatin immunoprecipitation for the analysis of chromatin modifications or factor binding, enzymatic digestions for chromatin structure assays, and RNA sequencing to assess gene expression changes after biological perturbations. To investigate the pattern and abundance of coverage signals across regions of interest, data are often visualized as profile plots of average signal or stacked rows of signal in the form of heatmaps. We found that available plotting software was either slow and laborious or difficult to use by investigators with little computational training, which inhibited wide data exploration. To address this need, we develop

SUBMITTER: Stempor P 

PROVIDER: S-EPMC5133382 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature