Acute Effects of Nitrogen Dioxide on Cardiovascular Mortality in Beijing: An Exploration of Spatial Heterogeneity and the District-specific Predictors.

ABSTRACT: The exploration of spatial variation and predictors of the effects of nitrogen dioxide (NO₂) on fatal health outcomes is still sparse. In a multilevel case-crossover study in Beijing, China, we used mixed Cox proportional hazard model to examine the citywide effects and conditional logistic regression to evaluate the district-specific effects of NO₂ on cardiovascular mortality. District-specific predictors that could be related to the spatial pattern of NO₂ effects were examined by robust regression models. We found that a 10 μg/m³ increase in daily mean NO₂ concentration was associated with a 1.89% [95% confidence interval (CI): 1.33-2.45%], 2.07% (95% CI: 1.23-2.91%) and 1.95% (95% CI: 1.16-2.72%) increase in daily total cardiovascul

SUBMITTER: Luo K 

PROVIDER: S-EPMC5133577 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature