AP1 transcription factors are required to maintain the peripheral taste system.

ABSTRACT: The sense of taste is used by organisms to achieve the optimal nutritional requirement and avoid potentially toxic compounds. In the oral cavity, taste receptor cells are grouped together in taste buds that are present in specialized taste papillae in the tongue. Taste receptor cells are the cells that detect chemicals in potential food items and transmit that information to gustatory nerves that convey the taste information to the brain. As taste cells are in contact with the external environment, they can be damaged and are routinely replaced throughout an organism's lifetime to maintain functionality. However, this taste cell turnover loses efficiency over time resulting in a reduction in taste ability. Currently, very little is known about the mechanisms that regulate the renewal and m

SUBMITTER: Shandilya J 

PROVIDER: S-EPMC5133999 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature