Ontology highlight
ABSTRACT:
SUBMITTER: Li C
PROVIDER: S-EPMC5134324 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Nature genetics 20160425 6
SWI/SNF-type chromatin remodelers, such as BRAHMA (BRM), and H3K27 demethylases both have active roles in regulating gene expression at the chromatin level, but how they are recruited to specific genomic sites remains largely unknown. Here we show that RELATIVE OF EARLY FLOWERING 6 (REF6), a plant-unique H3K27 demethylase, targets genomic loci containing a CTCTGYTY motif via its zinc-finger (ZnF) domains and facilitates the recruitment of BRM. Genome-wide analyses showed that REF6 colocalizes wi ...[more]