Atherosclerotic Plaques in the Aortic Arch and Subclinical Cerebrovascular Disease.

ABSTRACT:

Background and purpose

Aortic arch plaque (AAP) is a risk factor for ischemic stroke, but its association with subclinical cerebrovascular disease is not established. We investigated the association between AAP and subclinical cerebrovascular disease in an elderly stroke-free community-based cohort.

Methods

The CABL study (Cardiovascular Abnormalities and Brain Lesions) was designed to investigate cardiovascular predictors of silent cerebrovascular disease in the elderly. AAPs were assessed by suprasternal transthoracic echocardiography in 954 participants. Silent brain infarcts and white matter hyperintensity volume (WMHV) were assessed by brain magnetic resonance imaging. The association of AAP thickness with silent brain infarcts and WMHV was evaluated by logistic regress

SUBMITTER: Tugcu A 

PROVIDER: S-EPMC5134895 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature