Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer.

ABSTRACT:

Background

Robust data on patient-reported outcome measures comparing treatments for clinically localized prostate cancer are lacking. We investigated the effects of active monitoring, radical prostatectomy, and radical radiotherapy with hormones on patient-reported outcomes.

Methods

We compared patient-reported outcomes among 1643 men in the Prostate Testing for Cancer and Treatment (ProtecT) trial who completed questionnaires before diagnosis, at 6 and 12 months after randomization, and annually thereafter. Patients completed validated measures that assessed urinary, bowel, and sexual function and specific effects on quality of life, anxiety and depression, and general health. Cancer-related quality of life was assessed at 5 years. Complete 6-year data were analyzed accord

SUBMITTER: Donovan JL 

PROVIDER: S-EPMC5134995 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature