Genetic architecture of nonadditive inheritance in Arabidopsis thaliana hybrids.

ABSTRACT: The ubiquity of nonparental hybrid phenotypes, such as hybrid vigor and hybrid inferiority, has interested biologists for over a century and is of considerable agricultural importance. Although examples of both phenomena have been subject to intense investigation, no general model for the molecular basis of nonadditive genetic variance has emerged, and prediction of hybrid phenotypes from parental information continues to be a challenge. Here we explore the genetics of hybrid phenotype in 435 Arabidopsis thaliana individuals derived from intercrosses of 30 parents in a half diallel mating scheme. We find that nonadditive genetic effects are a major component of genetic variation in this population and that the genetic basis of hybrid phenotype can be mapped using genome-wide association (G

SUBMITTER: Seymour DK 

PROVIDER: S-EPMC5135357 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature