Reduced impact of renal failure on the outcome of patients with alcoholic liver disease undergoing liver transplantation.

ABSTRACT:

Background & aims

Pretransplant renal failure is commonly reported to be a poor prognostic indicator affecting survival after liver transplantation (LT). However, whether the impact of renal failure on patient outcome varies according to the aetiology of the underlying liver disease is largely unknown.

Methods

We investigated the association between renal failure at the time of LT and patient outcome in patients with alcoholic liver disease (ALD) (n = 6920), non-alcoholic steatohepatitis (NASH) (n = 2956) and hepatitis C (HCV) (n = 14 922) using the United Network for Organ Sharing (UNOS) database between February 2002 and December 2013. A total of 24 798 transplant recipients were included.

Results

The presence of renal failure was more frequently seen in patients wi

SUBMITTER: Cheong J 

PROVIDER: S-EPMC5136341 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature