A Fragmentation Study on Four Unusual Secoiridoid Trimers, Swerilactones H-K, by Electrospray Tandem Mass Spectrometry.

ABSTRACT: Swerilactones H-K (1-4) as four unprecedented secoiridoid trimers represent a new type of natural product, which has attracted much interest of natural chemists due to their novel skeletons and promising bioactivity. In order to well understand their MS fragmentation behaviors, they were investigated by electrospray ionization ion-trap time-of-flight multistage product ion mass spectrometry (ESI-IT-TOF-MS ⁿ ) for the first time. The protonated molecules ([M+H]⁺) of swerilactones J and K, and deprotonated molecules ([M-H]^-) of swerilactones H, J and K were readily observed in the conventional single-stage mass spectra (MS); however only the [M+Cl]^- ion for swerilactone I was obtained in negative mode. Based on the MS ⁿ study, the fragme

SUBMITTER: Geng CA 

PROVIDER: S-EPMC5136375 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature