Quantitative assessment of device-clot interaction for stent retriever thrombectomy.

ABSTRACT:

Purpose

Rapid revascularization in emergent large vessel occlusion with endovascular embolectomy has proven clinical benefit. We sought to measure device-clot interaction as a potential mechanism for efficient embolectomy.

Methods

Two different radiopaque clot models were injected to create a middle cerebral artery occlusion in a patient-specific vascular phantom. A radiopaque stent retriever was deployed within the clot by unsheathing the device or a combination of unsheathing followed by pushing the device (n=8/group). High-resolution cone beam CT was performed immediately after device deployment and repeated after 5 min. An image processing pipeline was created to quantitatively evaluate the volume of clot that integrates with the stent, termed the clot integration factor

SUBMITTER: van der Marel K 

PROVIDER: S-EPMC5136713 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature